The focus of lab is on “One Health Trio” to develop a healthy and sustainable community through basic and translational research in public health. Major themes of lab include COVID-19 and public health research, CRISPR-based field deployable diagnostics for infectious and genetic diseases, mother-child health diseases, zoonotic and nutritional diseases, and AMR alternative therapeutics. Additionally, education-policy awareness and educational reforms in post-COVID era are the targeted areas.

Publications:

1. Gull S, Farooq K, Tayyeb A, Arshad MI, Shahzad N., 2022, Ethanolic extracts of Pakistani euphorbiaceous plants induce apoptosis in breast cancer cells through induction of DNA damage and caspase-dependent pathway, Gene, 824, 146401
2. Saleem MU, Muhammad F, Sharif A, Arshad MI, Akhtar K, Javed Y, Akhtar B., 2022, Methotrexate-loaded biodegradable nanoparticles exert anti-arthritic effect by downregulating pro-inflammatory cytokines in Freund’s complete adjuvant-induced arthritic rats, Inflammopharmacology, April, 15, 0-0
3. Ishaq K, Ahmad A, Rafique A, Aslam R, Ali S, Shahid MA, Sarwar N, Aslam MA, Aslam B and Arshad MI, 2022, Occurrence and Antimicrobial Susceptibility of Proteus mirabilis from Chicken Carcass., Pakistan Veterinary Journal, April, 20, 0-4
4. Farooq M, Arshad MI and Usman M, 2022, Towards universal health coverage in Pakistan: Challenges ahead, The Lancet Regional Health Southeast Asia, May, 05, 0-2
5. Hussain Z, Khan JA, Arshad MI, Muhammad F, Abbas RZ., 2021, Protective Effects of Cinnamon, Cinnamaldehyde and Kaempferol against Acetaminophen-Induced Acute Liver Injury and Apoptosis in Mouse Model, Pakistan Veterinary Journal, 41(1), 25-32
6. Khan HA, Munir T, Khan JA, Shafia Tehseen Gul A-H, Ahmad MZ, Aslam MA, Umar MN, Arshad MI., 2021, IL-33 ameliorates liver injury and inflammation in Poly I:C and Concanavalin-A induced acute hepatitis, Microbial Pathogenesis, 150, 104716
7. Hussain Z, Khan JA, Arshad MI, Muhammad F, Abbas RZ., 2021, Comparative characterization of cinnamon, cinnamaldehyde and kaempferol for phytochemical, antioxidant and pharmacological properties using acetaminophen-induced oxidative stress mouse model, Boletin Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromáticas (BLACPMA), 20 (4), 339-350
8. Ahmad A, Ishtiaq SM, Khan JA, Aslam R, Ali S, Arshad MI., 2021, COVID-19 and comorbidities of hepatic diseases in a global perspective, World Journal of Gastroenterology, 27(13), 1296-1310
9. Gul ST, Saleemi MK, Waheed N, Arshad MI, Maqbool B, Khatoon A and Khan A., 2021, Salmonella typhimurium (A Zoonotic Threat) Prevailing in Commercial Poultry in Pakistan as Diagnosed by PCR and Loop-Mediated Isothermal Amplification (LAMP) Assay, Sylwan, 165 (7), 56-77
10. Aslam B, Arshad MI, Aslam MA, Muzammil S, Siddique AB, Yasmeen N, Khurshid M, Rasool M, Ahmad M, Rasool MH, Fahim M, Hussain R, Xia X, Baloch Z., 2021, Bacteriophage Proteome: Insights and Potentials of an Alternate to Antibiotics, , Infectious Diseases and Therapy, 10(3), 1171-1193
11. Ahmad A, Sarwar N, Aslam R, Ali S, Aslam B, Arshad MA, Hameed H, Arshad MI., 2021, Pattern of clinical drug resistance and occurrence of Gram negative bacterial neonatal sepsis at a tertiary care hospital, Pakistan Journal of Pharmaceutical Sciences, Vol.34, No, pp.1873-18
12. Shakir MZ, Rizvi F, Javed MT, Arshad MI., 2021, Seroprevalence and pathological studies of Salmonella infection in commercial white layer birds, Microbial Pathogenesis, 159, 105146
13. Aslam B, Khurshid M, Arshad MI, Muzammil S, Rasool M, Yasmeen N, Shah T, Chaudhry TH, Rasool MH, Shahid A, Xueshan X, Baloch Z., 2021, Antibiotic Resistance: One Health One World Outlook, Frontiers in Cellular and Infection Microbiology, 25;11, 771510
14. Mohyuddin MT, Muhammad G, Deeba F, Arshad MI., 2020, Therapeutic evaluation of autogenous mastitis vaccine alone and in combination with routine therapy in subclinical mastitis, Pakistan Journal of Agriculture Sciences, Vol. 57(4), 957-961
15. Manzoor A Muhammad G, Deeba F, Arshad MI., 2020, Therapeutic evaluation of an out of the box oral non-antibiotic formulation against clinical mastitis in buffalos, Pakistan Journal of Agriculture Sciences, Vol. 57(1), 269-274
16. Hussain I, Tasneem F, Gilani US, Arshad MI, Farhan Ul Haque M, Abbas Z, Umer M, Shahzad N., 2020, , Human BK and JC Polyomavirus: Molecular insights and prevalence in Asia, Virus Research, 278, 197860
17. Asghar S, Khan JA, Mahmood MS, Arshad MI., 2020, A cross-sectional study of group B Streptococcus associated sepsis, co-infections and antibiotic susceptibility profile in neonates in Pakistan, Advances in Neonatal Care, 20(4), E59-E69
18. Aslam B, Chaudhry TH, Arshad MI, Alvi RF, Shahzad N, Yasmeen N, Idris A, Rasool MH, Khurshid M, Ma Z, Call DR, Baloch Z., 2020, The First blaKPC Harboring Klebsiella pneumoniae ST258 Strain Isolated in Pakistan, Microbial Drug Resistance, 26(7), 783-786
19. Hussain A, Wu T, Fan L, Wang Y, Muhammad FK, Jiang N, Gao L, Li K, Gao Y, Liu C, Cui H, Pan Q, Zhang Y, Aslam A, Muti-Ur-Rehman K, Arshad MI, Abdullah HM, Wang X, Qi Xiao-Le Q., 2020, The circulation of unique reassortment strains of infectious bursal disease virus in Pakistan, Journal of Integrative Agriculture, 19(7), 1867-1875
20. Samad A, Bukhari AA, Sartaj S, Fayyaz N, Akhter N, Naeem N, Alam ME, Arshad MI., 2020, Tuberculous mastitis in females of South Punjab: a clinicopathological analysis of ten years from Pakistan, Biomedica, 36 (1), 30-37
21. Chaudhry TH, Aslam B, Arshad MI, Alvi RF, Muzammil S, Yasmeen N, Aslam MA, Khurshid M, Rasool MH, Baloch Z., 2020, Emergence of blaNDM-1 Harboring Klebsiella pneumoniae ST29 and ST11 in Veterinary Settings and Waste of Pakistan, Infection and Drug Resistance, 13, 3033-3043
22. Yaseen K, Sajid MS, Arshad MI, Aslam R, Ali S, Saqib M, Akram W, Abbas H, Malik A, Khalid U, Raza FA., 2020, Metagenomics of mosquito-borne flaviviruses in various geoclimatic districts of Punjab, Pakistan, Pakistan Veterinary Journal, 40(4), 407-412
23. Arshad MI, Khan HA, Aslam B, Khan JA., 2020, Appraisal of One Health approach amid COVID-19 and zoonotic pandemics: insights for policy decision, Tropical Animal Health and Production, 18;53(1), 11
24. Gilani US, Memoona, Rasheed A, Shahid M, Tasneem F, Arshad MI, Rashid N, Shahzad N., 2019, The implication of CRISPR/Cas9 genome editing technology in combating human oncoviruses, Journal of Medical Virology, 91(1), 1-13 Hussain Z, Khan JA, Arshad A, Asif P, Rashid H, Arshad MI., 2019, Protective effects of Cinnamomum zeylanicum L. (Darchini) in acetaminophen-induced oxidative stress, hepatotoxicity and nephrotoxicity in mouse model, Biomedicine & Pharmacotherapy, 109, 2285-2292
25. Musaddaq G, Shahzad N, Ashraf MA, Arshad MI., 2019, Circulating liver-specific microRNAs as non-invasive diagnostic biomarkers of hepatic diseases in human, Biomarkers, 24(2), 103-109
26. Chaudhry TA, Aslam B, Arshad MI, Nawaz Z, Waseem M., 2019, Occurrence of ESBL-producing Klebsiella pneumoniae in hospital settings and waste, Pakistan Journal of Pharmaceutical Sciences, 32(2 (Supp, 773-778
27. Naeem F, Anjum FR, Arshad MA, Bukhari AA, Aslam B, Khan JA, Arshad MI., 2019, Isolation and antibiotic sensitivity pattern of drug resistant bacteria in ulcerative foot of type 2 diabetic patients, , Pakistan Journal of Pharmaceutical Sciences, Vol.32, No, pp.1843-18
28. Waqar N, Amin Q, Munir T, Ikram MS, Shahzad N, Mirza A, Ali A, Arshad MI., 2019, cross-sectional study of methicillin-resistant Staphylococcus aureus at the equine-human interface, Tropical Animal Health and Production, 51(7), 1927-1933
29. Masood F, Abdullah RM, Anam S, Arshad MI, Anjum FR., 2019, , Occurrence and antibiogram of enteric bacterial isolates from stool samples of gastroenteritis children under 5 years of age in district Faisalabad, Pakistan, Pure and Applied Biology, 8(3), 2087-2094
30. Ishtiaq SM, Rashid H, Hussain Z, Arshad MI, Khan JA., 2019, Adiponectin and PPAR: A setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease, Reviews in Endocrinology Metabolic Disorders, 20(3), 253-261 Naveed A, Rahman SU, Arshad MI, Bilal Aslam., 2018, Recapitulation of the anti-Idiotype antibodies as vaccine candidate, Translational Medicine Communications, 3, 1
31. Ishtiaq SM, Khan JA, Arshad MI., 2018, Psychosocial-Stress, Liver Regeneration and Weight Gain: a Conspicuous Pathophysiological Triad,, Cellular Physiology and Biochemistry, 20;46(1), 08-Jan
32. Pervez A, Anjum FR, Bukhari AA, Anam S, Rahman SU, Arshad MI., 2018, Isolation and Virulence Genes Characterization of Diarrheagenic Escherichia coli from Calves,, Pakistan Veterinary Journal, 38(2), 133-136 Ashraf MA., Arshad MI., Rahman SU, Khan A., 2018, Characterization of moderately thermostable ?-amylase-producing Bacillus licheniformis from decaying potatoes and sweet potatoes, BioResources, 13(3), 4931-4945 Aslam B, Wang W, Arshad MI, Khurshid M, Muzammil S, Rasool MH, Nisar MA, Alvi RF, Aslam MA, Qamar MU, Salamat MKF, Baloch Z., 2018, Antibiotic resistance: a rundown of a global crisis, Infection and Drug Resistance, 11, 1645-1658
33. Naveed A, Rahman SU, Arshad MI, Aslam B., 2018, Foot-and-Mouth Disease: A Strategic Analysis for the Control of Disease, Vaccines & Vacccination, 3(2), 000125
34. Naveed A, Rahman SU, Arshad MI, Aslam B., 2018, Immune modulatory potential of anti-idiotype antibodies as surrogate of foot-and-mouth disease virus antigen, mSphere, 3(5), ). pii: e0
35. Hussain I, Tasneem F, Umer M, Pervaiz A, Raza M, Arshad MI, Shahzad N., 2017, Specific and quantitative detection of Human polyomaviruses BKPyV and JCPyV in the healthy Pakistani population, Virology Journal, 24;14 (1), 86 Khan HA, Ahmad MZ, Khan JA, Arshad MI., 2017, , Crosstalk of liver immune cells and cell death mechanisms in different murine models of liver injury and its clinical relevance, Hepatobiliary & Pancreatic Diseases International, 16(3), 245-256
36. Carrière V, Arshad MI, Le Seyec J, Lefevre B, Farooq M, Jan A, Manuel C, Touami-Bernard L, Lucas-Clerc C, Genet V, Gascan H, Girard JP, Chalmel F, Lamontagne L, Piquet-Pellorce C, Samson M., 2017, Endogenous IL-33 deficiency exacerbates liver injury and increases hepatic influx of neutrophils in acute murine viral hepatitis, Mediators of Inflammation, 04-May, 1359064
37. Ali S, Arshad MI, Akhtar F, Saqib M, Aslam R, Abbas G, Ashraf M, Rahman SU., 2017, Seroprevalence and risk factor association of feline immunodeficiency virus in cats, Pakistan Veterinary Journal, 37(3), 368-371
38. Arshad MI, Khan HA, Noel G, Piquet-Pellorce C, Samson M., 2016, Potential therapeutic aspects of alarmin cytokine IL-33 or its inhibitors in various diseases16, Clinical Therapeutics, 38(5), 1000-1016.
39. Noel G, Arshad MI, Filliol A, Genet V, Rauch M, Lucas-Clerc C, Lehuen A, Girard JP, Piquet-Pellorce C, Samson M., 2016, Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cells liver infiltration, American Journal of Physiology Gastrointestinal Liver Physiology, 311(2), G313-23
40. Arshad MI, Khan HA, Piquet-Pellorce C, Samson M., 2016, Interleukin-33 and its Soluble Receptor ST2 as Non-Invasive Biomarkers of Human Hepatitis, JSM Hepatitis, 1(1), 1003
41. Bukhari AA, Arshad MI, Raza S, Azam M, Rahman SU, Mohsin M., 2016, Emergence of extended spectrum beta-lactamases-producing strains belonging to cefotaxime-M-1 class from intensive care units patients and environmental surfaces in Pakistan, International Journal of One Health, 2, 69-74
42. Roston, O. , M. I. Arshad, C. Piquet-Pellorce, F. Robert-Gangneux, J. P. Gangneux, and M. Samson, 2015, Crucial and diverse role of IL-33/ST2 axis in infectious diseases, Infection and Immunity, 83(5), 1738-48
43. Rostan O, Arshad MI, Piquet-Pellorce C, Robert-Gangneux F, Gangneux JP, Samson M., 2015, Crucial and diverse role of IL-33/ST2 axis in infectious diseases11, Infection and Immunity, 83(5), 1738-48
44. Arshad MI, Piquet-Pellorce C, Filliol A, L’Helgoualc’h A, Lucas-Clerc C, Jouan-Lanhouet S, Dimanche-Boitrel MT, Samson M., 2015, The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulated the cytokine IL-33 expression in liver, Journal of Molecular Medicine (Berl), 93(8), 867-78
45. Basset L, Chevalier S, Danger Y, Arshad MI, Piquet-Pellorce C, Gascan H, Samson M., 2015, Interleukin-27 and IFN? regulate the expression of CXCL9, CXCL10, and CXCL11 in hepatitis13, Journal of Molecular Medicine (Berl), 93(12), 1355-67
46. Arshad MI, Guihard P, Danger Y, Noel G, Le Seyec J, Boutet MA, Richards C, L'Helgoualc'h A, Genet V, Lucas-Clerc C, Gascan H, Blanchard F, Piquet-Pellorce C, Samson M., 2015, Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes, American Journal of Physiology Gastrointestinal Liver Physiology, 1;309(7), G542-53
47. Arshad MI, Noel G, Filliol A, Genet V, Lucas-Clerc C, Girard JP, Piquet-Pellorce C, Samson M., 2015, IL-33 knockout mice are sensitized to severe ConA liver injury but not CCl4-mediated liver injury15, Journal of Hepatology, 62, S487-S488
48. Arshad MI, Filliol A, Genet V, Lucas-Clerc C, Girard J.P, Piquet-Pellorce C and Samson M. , 2014, Deficiency of IL-33 sensitizes to severe liver injury induced by ConA but not by CCl4 in mice., Journal of Hepatology, 60, S67-S214
49. Arshad MI, Filliol A, Genet V, Lucas-Clerc C, Girard J.P, Piquet-Pellorce C, Samson M., 2014, Deficiency of IL-33 sensitizes to severe liver injury induced by ConA but not by CCl4 in mice, Journal of Hepatology, 60, S67-S214,
50. Arshad MI, Patrat-Delon S, Piquet-Pellorce C, L, 2013, Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of Hepatitis. , PLoS One, 8(9), e74278
51. Arshad MI, Patrat-Delon S, Piquet-Pellorce C, L’Helgoualc’h A, Rauch M, Genet V, Lucas-Clerc C, Bleau C, Lamontagne L, Samson M., 2013, Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of Hepatitis9, PLoS One, 13; 8(9), e74278
52. Arshad MI, Piquet-Pellorce C, Samson M. , 2012, IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology. , Liver International, 32(8), 1200-10
53. Hussain I, Mahmood MS, Arshad MI, Akhtar M, Mahmood F, Rafique A. , 2012, Immune system dysfunction in broiler chickens experimentally inoculated with fowl adenovirus serotype-4 associated with inclusion body hepatitis hydropericardium syndrome. , Turkish Journal of Veterinary and Animal Sciences, 36(3), 223-230
54. Arshad MI, Piquet-Pellorce C, L, 2012, TRAIL, but not FasL and TNFa, regulates IL-33 expression in murine hepatocytes during acute hepatitis., Hepatology, 56(6), 2353-62
55. Jouan-Lanhouet S, Arshad MI, Piquet-Pellorce C, Martin-Chouly C, Le Moigne-Muller G, Van Herreweghe F, Takahashi N, Sergent O, Lagadic-Gossmann D, Van, 2012, TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation. , Cell Death and Differentiation, 19(12), 2003-2014
56. Arshad MI, Patrat-Delon S, L, 2012, NKT cells and TRAIL induce hepatocyte IL-33 in murine acute hepatitis. , Cytokine, 59(3), 549
57. Arshad MI, Piquet-Pellorce C, Samson M., 2012, IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology, Liver International, 32(8), 1200-10
58. Hussain I, Mahmood MS, Arshad MI, Akhtar M, Mahmood F, Rafique A., 2012, Immune system dysfunction in broiler chickens experimentally inoculated with fowl adenovirus serotype-4 associated with inclusion body hepatitis hydropericardium syndrome5, Turkish Journal of Veterinary and Animal Sciences, 36(3, 223-230
59. Arshad MI, Piquet-Pellorce C, L’Helgoualc’h A, Rauch M, Patrat-Delon S, Ezan F, Lucas-Clerc C, Nabti S, Lehuen A, Javier Cubero F, Girard J-P, Trautwein C, Samson M., 2012, TRAIL, but not FasL and TNF?, regulates IL-33 expression in murine hepatocytes during acute hepatitis, , Hepatology, 56(6), 2353-62
60. Jouan-Lanhouet S, Arshad MI, Piquet-Pellorce C, Martin-Chouly C, Le Moigne-Muller G, Van Herreweghe F, Takahashi N, Sergent O, Lagadic-Gossmann D, Vandenabeele P, Samson M, Dimanche-Boitrel MT., 2012, TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation,, Cell Death and Differentiation, 19(12), 2003-2014 Arshad MI, Patrat-Delon S, L’Helgoualc’h A, Rauch M, Lucas-Clerc C, Girard J-P, Piquet-Pellorce C, Samson M., 2012, NKT cells and TRAIL induce hepatocyte IL-33 in murine acute hepatitis, Cytokine, 59(3), 549
61. Le Goffic R, Arshad MI, Rauch M, L, 2011, Influenza virus infection induces IL-33 in murine lungs. , American Journal of Respiratory Cell and Molecular Biology,, 45, 1125–1132
62. Arshad MI, Rauch M, L, 2011, NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis. , European Journal of Immunology, 41(8), 2341-8
63. Le Goffic R, Arshad MI, Rauch M, L’Helgoualc’h A, Delmas B, Piquet-Pellorce C, Samson M., 2011, Influenza virus infection induces IL-33 in murine lungs, American Journal of Respiratory Cell and Molecular Biology, 45, 1125–1132 Arshad MI, Rauch M, L’Helgoualc’h A, Julia V, Leite-de-Moraes MC, Lucas-Clerc C, Piquet-Pellorce C, Samson M., 2011, NKT cells are required to induce high IL-33 expression in hepatocytes during ConA-induced acute hepatitis, European Journal of Immunology, 41(8), 2341-8
64. Mahmood MS, Hussain I, Arshad MI, Ali S, Aktar M, Khan A, Mahmood F., 2009, Seasonal Prevalence of Campylobacter Species in Milk and Milk Products in Pakistan. , Pakistan J. Zool. , 9, 227-231
65. Hussain I, Arshad MI, Mahmood MS, Akhtar M, Ali S, Khan A and Mahmood F. , 2009, Clinico-epidemiological, microbiological and antibiogram studies of Corynebacterium bovis associated with mastitis in buffaloes (Bubalus bubalis). , Pakistan J Zool., 9, 818-823
66. Hussain I, Arshad MI, Mahmood MS, Akhtar M. , 2008, Seroprevalence of Brucellosis in Human, Cattle, and Buffalo Populations in Pakistan. , Turkish Journal of Veterinary and Animal Sciences, 32 (4), 315-318
67. Hussain I, Arshad MI, Mahmood MS, Akhtar M., 2008, Seroprevalence of Brucellosis in Human, Cattle, and Buffalo Populations in Pakistan, Turkish Journal of Veterinary and Animal Sciences, 32 (4), 315-318.